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KMID : 0363620100310010162
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Journal of Korean Oriental Medicine
2010 Volume.31 No. 1 p.162 ~ p.173
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Effects of Herb Medication on Dry Cough, a Common Side Effect Caused by Angiotensin Converting Enzyme (ACE) Inhibitor
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Kim Hyun-Jin
Kang Rae-Yeop
Han Hyo-Jung
Park Eun-Young
Jang Jeong-A
Seo Ho-Seok
Park So-Ae
Kim Jin-Won
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Abstract
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Objectives: In order to confirm a remedial effect and related influence of the clinic treatment by prescribing herb medicines to hypertensives experiencing angiotensin converting enzyme (ACE) inhibitor dosage and suffering from common side effect generally known as dry cough.
Methods: 1. We selected the 19 patients who visited National Oriental Medical Center, from August 21, 2007 to August 16, 2008 and suffering from dry cough caused by taking ACE inhibitor, with no other possible diseases causing dry cough. 2. We separated the 19 patients into two groups (Type 1: Bi-Qi hie (脾氣虛) group prescribed Samchuljojung-tang & Type 2: Qi-hie dam-wul (氣虛痰鬱) group prescribed Samsoumgamibang). 3. We then observed the symptom level and post-treatment effect, and recorded changes of dry cough intensity level for each group.
Results: 1. Type 1: In the survey of 12 patients, initial level recorded 16.33 at entry diagnosis, and next level meant changing of symptoms, recorded as 2.75 at Stage 1 and reaching 3.33 at Stage 2. 2. Type 2: 7 patients, with initial level recorded as 18.71 at entry diagnosis, and 1.86 at Stage 1 and reaching to 3.29 at Stage 2. 3. No additional prescriptions were issued at Stage 2 or afterwards, and final result indicates that the mean value ended at 3.95 in the total group.
Conclusions: It is concluded that there is a significant remedial effect and related influence of the clinic treatment between the Oriental medicine treatment and one of the common side effects of ACE inhibitor, dry cough.
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KEYWORD
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ACE Inhibitor, dry cough, Samchuljojung-tang, Samsoumgamibang
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